SCHEMBL9474707

SCHEMBL9474707

Cc1ccc(C)c(/C=C/c2ccccc2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.62
PTGS1 P23219 3/20 0.62
PTGS2 P35354 3/20 0.62
LMNA P02545 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ALDH1A1 P00352 2/20 0.50
TTR P02766 1/20 0.50
NFE2L2 Q16236 5/20 0.47
CHAT P28329 1/20 0.47
TUBB4A P04350 1/20 0.45
TUBB P07437 1/20 0.45
TUBA3C P0DPH7 1/20 0.45
TUBA1B P68363 1/20 0.45
TUBA4A P68366 1/20 0.45
TUBB4B P68371 1/20 0.45
TUBB3 Q13509 1/20 0.45
TUBB2A Q13885 1/20 0.45
TUBB8 Q3ZCM7 1/20 0.45
TUBA3E Q6PEY2 1/20 0.45
TUBA1A Q71U36 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9473335 1.00 ALOX5 (0.62) ALOX5PTGS1PTGS2LMNASMN1; SMN2
SCHEMBL16105742 1.00 ALOX5 (0.62) ALOX5PTGS1PTGS2LMNASMN1; SMN2
SCHEMBL13017390 0.85 ALOX5 (0.51) ALOX5PTGS1PTGS2LMNASMN1; SMN2
SCHEMBL30175764 0.84 PTGS1 (0.62) ALOX5PTGS1PTGS2LMNASMN1; SMN2
SCHEMBL11414757 0.84 PTGS1 (0.62) ALOX5PTGS1PTGS2LMNASMN1; SMN2
SCHEMBL16105505 0.84 NFE2L2 (0.51) ALOX5PTGS1PTGS2LMNASMN1; SMN2
SCHEMBL6936635 0.84 PTGS1 (0.62) ALOX5PTGS1PTGS2LMNASMN1; SMN2
SCHEMBL6547378 0.84 NFE2L2 (0.51) ALOX5PTGS1PTGS2LMNASMN1; SMN2
SCHEMBL16105579 0.84 NFE2L2 (0.51) ALOX5PTGS1PTGS2LMNASMN1; SMN2
SCHEMBL19583367 0.83 TTR (0.57) ALOX5PTGS1PTGS2ALDH1A1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404221-B2 Methods of arene alkenylation UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-09-02 US disclosed
US-20230234900-A1 METHODS OF ARENE ALKENYLATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2023-07-27 US disclosed
US-9419307-B2 Organic electrolyte and organic electrolyte storage battery JX NIPPON OIL & ENERGY CORPORATION (JP) 2016-08-16 US disclosed
US-20150004484-A1 ORGANIC ELECTROLYTE AND ORGANIC ELECTROLYTE STORAGE BATTERY JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-01-01 US disclosed
US-20140370375-A1 ORGANIC ELECTROLYTE AND ORGANIC ELECTROLYTE STORAGE BATTERY JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-12-18 US disclosed
EP-2797154-A1 ORGANIC ELECTROLYTE, AND ORGANIC ELECTROLYTE STORAGE BATTERY JX Nippon Oil & Energy Corporation (JP) 2014-10-29 EP disclosed
EP-2797153-A1 ORGANIC ELECTROLYTE, AND ORGANIC ELECTROLYTE STORAGE BATTERY JX Nippon Oil & Energy Corporation (JP) 2014-10-29 EP disclosed
US-20140302387-A1 ORGANIC ELECTROLYTE AND ORGANIC ELECTROLYTE STORAGE BATTERY JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-10-09 US disclosed
EP-2784868-A1 ORGANIC ELECTROLYTE AND ORGANIC ELECTROLYTE STORAGE BATTERY JX Nippon Oil & Energy Corporation (JP) 2014-10-01 EP disclosed
US-5210219-A Bis-sulfonium salts of 2,5-dimethylstilbene UNITED STATES OF AMERICA, THE, AS REPRESENTED BY THE SECRETARY OF THE NAVY 1993-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234900-A1 METHODS OF ARENE ALKENYLATION CYBB, CBR3, AHR ALOX5 117/4885PTGS1 2007/4885PTGS2 1773/4885
US-12404221-B2 Methods of arene alkenylation CYBB, CBR3, AHR ALOX5 117/4885PTGS1 2007/4885PTGS2 1773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.