Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.44 |
| ▸ | MAOB | P27338 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | UNG | P13051 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317305 | 0.81 | ALDH1A3 (0.55) | ALDH1A1KMT2AMEN1DRD1SMN1; SMN2 | |
| SCHEMBL17828384 | 0.80 | MAOA (0.48) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL17828390 | 0.80 | MAOA (0.48) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL11290007 | 0.80 | SRC (0.46) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL17828395 | 0.80 | MAOA (0.48) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL10591781 | 0.78 | MAOA (0.47) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL11093524 | 0.76 | MAOA (0.44) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL2174551 | 0.76 | SMN1; SMN2 (0.55) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL1011104 | 0.76 | SMN1; SMN2 (0.55) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL29951428 | 0.75 | ALDH1A3 (0.60) | MAOAMAOBNPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336374-A | HYPOGLYCEMIC AGENTS | NIPPON SHINYAKU CO., LTD. (JP) | 1982-06-22 | — | — | US | disclosed |