Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11289744 | 0.98 | GRM7 (0.44) | GRM7HRH3MTNR1AMTNR1BABCB11 | |
| SCHEMBL11005581 | 0.86 | KDM1A (0.54) | GRM7HRH3MTNR1AMTNR1BNPC1 | |
| Hydrochloric Acid SCHEMBL11005579 | 0.84 | KDM1A (0.52) | GRM7HRH3MTNR1AMTNR1BNPC1 | |
| SCHEMBL9057495 | 0.79 | GRM7 (0.55) | GRM7HRH3MTNR1AMTNR1BNPC1 | |
| SCHEMBL9057496 | 0.79 | GRM7 (0.55) | GRM7HRH3MTNR1AMTNR1BNPC1 | |
| SCHEMBL7139021 | 0.78 | KDM1A (0.53) | GRM7HRH3MTNR1AMTNR1BNPC1 | |
| SCHEMBL2310770 | 0.77 | L3MBTL1 (0.41) | TSHRMAPT | |
| SCHEMBL10652307 | 0.77 | L3MBTL1 (0.41) | TSHRMAPT | |
| Hydrochloric Acid SCHEMBL6052700 | 0.76 | KDM1A (0.51) | GRM7HRH3MTNR1AMTNR1BNPC1 | |
| SCHEMBL7909264 | 0.76 | ATM (0.52) | GRM7HRH3MTNR1AMTNR1BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051391-A1 | Bicyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-05-12 | — | — | EP | disclosed |