Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283527 | 0.93 | HTT (0.36) | TBXA2RFFAR1ADRB3 | |
| SCHEMBL11285934 | 0.89 | TBXA2R (0.35) | SLC6A4HTR2AKCNH2TBXA2RSLC6A3 | |
| SCHEMBL11283323 | 0.87 | TBXA2R (0.36) | SLC6A4HTR2AKCNH2TBXA2RSLC6A3 | |
| SCHEMBL11290231 | 0.85 | PMP22 (0.50) | PMP22ADRB3MEN1KMT2A | |
| SCHEMBL11280676 | 0.83 | ALDH1A1 (0.36) | SLC6A4HTR2AKCNH2TBXA2RFFAR1 | |
| SCHEMBL11287411 | 0.81 | TBXA2R (0.37) | TBXA2RADRB3KMT2AACHE | |
| SCHEMBL11277075 | 0.81 | TBXA2R (0.37) | TBXA2RADRB3KMT2AACHE | |
| SCHEMBL11290647 | 0.78 | MAPT (0.38) | SLC6A4HTR2AKCNH2TBXA2RSLC6A3 | |
| SCHEMBL11283535 | 0.78 | PMP22 (0.45) | TBXA2RPMP22ADRB3MEN1KMT2A | |
| SCHEMBL11284482 | 0.78 | TBXA2R (0.37) | TBXA2RPMP22ADRB3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |