Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288228 | 0.85 | ENPP2 (0.38) | TBXA2R | |
| SCHEMBL11290193 | 0.83 | SLC6A4 (0.36) | HTR2ASLC6A4KCNH2MEN1KMT2A | |
| SCHEMBL11281999 | 0.80 | HIF1A (0.52) | ALDH1A1KCNH2ADRB2ADRB1ADRB3 | |
| SCHEMBL11290231 | 0.80 | PMP22 (0.50) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL11280679 | 0.80 | ADRB2 (0.39) | ALDH1A1MEN1KMT2AADRB2ADRB1 | |
| SCHEMBL11428877 | 0.78 | ACHE (0.37) | ALDH1A1HTR2ASLC6A4KCNH2POLB | |
| SCHEMBL11283527 | 0.77 | HTT (0.36) | TBXA2RADRB2FFAR1ADRB1ADRB3 | |
| SCHEMBL11289567 | 0.76 | ALDH1A1 (0.43) | ALDH1A1POLBADRB2LMNACYP3A4 | |
| SCHEMBL11285934 | 0.76 | TBXA2R (0.35) | ALDH1A1HTR2ASLC6A4KCNH2TBXA2R | |
| SCHEMBL11282043 | 0.75 | TBXA2R (0.38) | HTR2ASLC6A4KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |