Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17471896 | 0.77 | NISCH (0.38) | NISCHHTR1DADRA2AADRA2BADRA2C | |
| SCHEMBL11410917 | 0.74 | NISCH (0.38) | NISCHHTR1DADRA2AADRA2BADRA2C | |
| SCHEMBL1194234 | 0.71 | TSHR (0.36) | — | |
| SCHEMBL17472382 | 0.70 | ADRA2A (0.33) | NISCHHTR1DADRA2AADRA2BADRA2C | |
| SCHEMBL7094563 | 0.68 | ADRA2A (0.47) | NISCHHTR1DADRA2AADRA2BADRA2C | |
| SCHEMBL6843923 | 0.68 | CNR2 (0.37) | — | |
| SCHEMBL17472347 | 0.68 | CXCR4 (0.34) | NISCHHTR1DADRA2AADRA2BADRA2C | |
| SCHEMBL1825440 | 0.67 | CHKA (0.38) | — | |
| SCHEMBL18993759 | 0.66 | CXCR4 (0.33) | NISCHHTR1DADRA2AADRA2BADRA2C | |
| SCHEMBL6694379 | 0.65 | BDKRB2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007438-B1 | SUBSTITUTED 2-PHENYLAMINO-2-IMIDAZOLINES, THEIR ACID ADDITION SALTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | C.H. BOEHRINGER SOHN (DE) | 1982-09-01 | — | — | EP | disclosed |