Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 12/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290241 | 1.00 | SLC6A1 (0.59) | SLC6A1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL7358276 | 0.93 | ALDH1A1 (0.63) | SLC6A1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL10964291 | 0.90 | SLC6A1 (0.73) | SLC6A1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL5164435 | 0.88 | SLC6A1 (0.78) | SLC6A1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL10968404 | 0.88 | SLC6A1 (0.78) | SLC6A1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL5164434 | 0.88 | SLC6A1 (0.78) | SLC6A1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL9773464 | 0.88 | SLC6A1 (0.66) | SLC6A1ALDH1A1KDM4EPTGS1PDE4A | |
| SCHEMBL9773356 | 0.88 | SLC6A1 (0.66) | SLC6A1ALDH1A1KDM4EPTGS1PDE4A | |
| SCHEMBL9773351 | 0.88 | SLC6A1 (0.66) | SLC6A1ALDH1A1KDM4EPTGS1PDE4A | |
| SCHEMBL9773348 | 0.88 | SLC6A1 (0.66) | SLC6A1ALDH1A1KDM4EPTGS1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066456-A1 | N-substituted azaheterocyclic carboxylic acids and their esters | SMITHKLINE BECKMAN CORPORATION (US) | 1982-12-08 | — | — | EP | disclosed |