Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102570 | 0.81 | TAAR1 (0.43) | TRPA1PSMB8PSMB5FDPSANPEP | |
| SCHEMBL4338140 | 0.80 | PSMB8 (0.44) | PSMB8PSMB5ANPEPMMEMEN1 | |
| SCHEMBL4333077 | 0.79 | PSMB8 (0.47) | PSMB8PSMB5ANPEPMMEALDH1A1 | |
| SCHEMBL11290360 | 0.79 | MEN1 (0.49) | TRPA1PSMB8PSMB5FDPSANPEP | |
| SCHEMBL4337718 | 0.77 | GRN (0.43) | TRPA1PSMB8PSMB5ANPEPMME | |
| SCHEMBL1153189 | 0.73 | ANPEP (0.40) | PSMB8PSMB5ANPEPMMEALDH1A1 | |
| SCHEMBL1153511 | 0.72 | LNPEP (0.44) | TRPA1ANPEPCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1153513 | 0.72 | LNPEP (0.44) | TRPA1ANPEPCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1153610 | 0.72 | MMP1 (0.42) | PSMB8PSMB5ANPEPMMEALDH1A1 | |
| SCHEMBL1153781 | 0.72 | PSEN1 (0.40) | PSMB8PSMB5ANPEPMMEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044158-A1 | Novel optically active imidazolidin-2-one derivatives and their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-01-20 | — | — | EP | claimed |