Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290058 | 0.89 | HDAC3 (0.31) | — | |
| SCHEMBL11349473 | 0.89 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1MAPTMEN1ALOX15 | |
| SCHEMBL11289099 | 0.88 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1MAPTMEN1ALOX15 | |
| SCHEMBL11299749 | 0.88 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1MAPTMEN1ALOX15 | |
| SCHEMBL11277898 | 0.86 | RAB9A (0.41) | ALDH1A1MAPTMEN1ALOX15MAPK1 | |
| SCHEMBL11297292 | 0.86 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1MAPTMEN1ALOX15 | |
| SCHEMBL11414665 | 0.85 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1MAPTMEN1ALOX15 | |
| SCHEMBL11314993 | 0.85 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1MAPTMEN1ALOX15 | |
| SCHEMBL11494654 | 0.85 | KMT2A (0.46) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11297070 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014167-B1 | Aniline derivatives with antifungal activity and process for their preparation | RHONE-POULENC AGROCHIMIE (FR) | 1982-06-30 | — | — | EP | disclosed |
| EP-0014167-A1 | Aniline derivatives with antifungal activity and process for their preparation | RHONE-POULENC AGROCHIMIE (FR) | 1980-08-06 | — | — | EP | disclosed |