Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | DAPK1 | P53355 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31745135 | 1.00 | MAPT (0.44) | MAPTMEN1KMT2AMAOAALDH1A1 | |
| SCHEMBL11289616 | 0.87 | MAOA (0.51) | MAPTMEN1KMT2AMAOAALDH1A1 | |
| SCHEMBL567474 | 0.82 | EGFR (0.54) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14537729 | 0.82 | EGFR (0.54) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10584436 | 0.81 | BCL2 (0.48) | MAPTMEN1KMT2AMAOAALDH1A1 | |
| Hydrochloric Acid SCHEMBL29658548 | 0.81 | EGFR (0.53) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL7460 | 0.81 | EGFR (0.53) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL27321737 | 0.81 | MEN1 (0.42) | MAPTMEN1KMT2AMAOAALDH1A1 | |
| SCHEMBL24612662 | 0.80 | MAPT (0.40) | MAPTMEN1KMT2AMAOAALDH1A1 | |
| SCHEMBL497017 | 0.80 | MAPT (0.40) | MAPTMEN1KMT2AMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007403-B1 | 5,12-DIHYDROXY-1,2,3,4,6,11-HEXAHYDRO-2,6,11-TRIOXONAPHTHACENES AND THEIR SYNTHESIS | THE UNIVERSITY OF KANSAS (US) | 1982-11-24 | — | — | EP | claimed |
| US-4244880-A | Anthracycline synthesis | UNIVERSITY OF KANSAS ENDOWMENT ASSOCIATION (US) | 1981-01-13 | — | — | US | claimed |
| EP-0007403-A1 | 5,12-dihydroxy-1,2,3,4,6,11-hexahydro-2,6,11-trioxonaphthacenes and their synthesis | THE UNIVERSITY OF KANSAS (US) | 1980-02-06 | — | — | EP | claimed |
| EP-0007403-B1 | 5,12-DIHYDROXY-1,2,3,4,6,11-HEXAHYDRO-2,6,11-TRIOXONAPHTHACENES AND THEIR SYNTHESIS | THE UNIVERSITY OF KANSAS (US) | 1982-11-24 | — | — | EP | disclosed |
| US-4244880-A | Anthracycline synthesis | UNIVERSITY OF KANSAS ENDOWMENT ASSOCIATION (US) | 1981-01-13 | — | — | US | disclosed |
| EP-0007403-A1 | 5,12-dihydroxy-1,2,3,4,6,11-hexahydro-2,6,11-trioxonaphthacenes and their synthesis | THE UNIVERSITY OF KANSAS (US) | 1980-02-06 | — | — | EP | disclosed |
| US-4021457-A | Intermediates for polycyclic quinonoid antibiotics | RESEARCH CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |