Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.30 |
| ▸ | NOS2 | P35228 | 2/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452401 | 0.67 | MAPT (0.39) | MAPTTDP1NOS3NOS2NOS1 | |
| SCHEMBL26598629 | 0.67 | MAPT (0.56) | MAPTTDP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4452403 | 0.67 | MAPT (1.00) | MAPTTDP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28267332 | 0.67 | MAPT (0.56) | MAPTTDP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL26598714 | 0.67 | MAPT (0.56) | MAPTTDP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8012292 | 0.66 | MAPT (0.39) | MAPTTDP1NOS3NOS2 | |
| SCHEMBL29724038 | 0.63 | MAPT (0.52) | MAPTTDP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2175144 | 0.63 | MAPT (0.52) | MAPTTDP1RAB9ANPC1NOS3 | |
| SCHEMBL15904245 | 0.62 | MAPT (0.50) | MAPTTDP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4198333 | 0.62 | MAPT (0.50) | MAPTTDP1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048538-A1 | Azo dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-03-31 | — | — | EP | disclosed |