Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15520859 | 0.82 | DHFR (0.32) | MAPTTDP1NOS3NOS2IMPDH2 | |
| SCHEMBL3781405 | 0.80 | NPC1 (0.41) | TDP1NOS3NOS2 | |
| SCHEMBL11418529 | 0.76 | — | — | |
| SCHEMBL10582024 | 0.74 | IMPDH2 (0.33) | IMPDH2 | |
| SCHEMBL9346680 | 0.74 | IMPDH2 (0.33) | IMPDH2 | |
| SCHEMBL10339189 | 0.70 | XDH (0.39) | MAPTTDP1IMPDH2 | |
| SCHEMBL456737 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL9301795 | 0.69 | GABRA1 (0.35) | MAPT | |
| SCHEMBL486583 | 0.69 | CASP1 (0.46) | IMPDH2 | |
| SCHEMBL369674 | 0.69 | CASP1 (0.40) | IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000032671-A1 | PROCESS FOR THE PRODUCTION OF DIKETO DINITRILES AND POLYMERS DERIVED THEREFROM | COGNIS CORPORATION (US) | 2000-06-08 | — | — | WO | disclosed |
| US-6048958-A | REACTION OF DIESTER WITH NITRILE TO FORM ALKALI METAL SALT AND ACIDIFICATION | HENKEL CORPORATION (US) | 2000-04-11 | — | — | US | disclosed |