SCHEMBL1129112

SCHEMBL1129112

CCCCOCCO[Si](OCCOCCCC)(OCCOCCCC)OCCOCCCC

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
CYP3A4 P08684 3/20 0.48
MEN1 O00255 1/20 0.44
THRB P10828 1/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 1/20 0.44
MAPT P10636 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
ALDH1A1 P00352 3/20 0.33
RARB P10826 1/20 0.33
CES2 O00748 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3963478 1.00 TSHR (0.50) TSHRCYP3A4MEN1THRBHTT
SCHEMBL7109465 0.93 TSHR (0.44) TSHRCYP3A4MEN1THRBHTT
SCHEMBL7109570 0.93 TSHR (0.44) TSHRCYP3A4MEN1THRBHTT
SCHEMBL7111658 0.88 TSHR (0.44) TSHRCYP3A4MEN1THRBHTT
SCHEMBL29164952 0.88 HTT (0.56) TSHRCYP3A4MEN1THRBHTT
SCHEMBL29164977 0.88 HTT (0.56) TSHRCYP3A4MEN1THRBHTT
SCHEMBL7110603 0.88 TSHR (0.44) TSHRCYP3A4MEN1THRBHTT
SCHEMBL20548379 0.83 HSD17B10 (0.35) TSHRCYP3A4MEN1THRBHTT
SCHEMBL49555 0.83 ADRB2 (0.45) TSHRCYP3A4THRBSMN1; SMN2HPGD
SCHEMBL1132722 0.83 TSHR (0.67) TSHRCYP3A4MEN1THRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8963413-B2 Device comprising an organic light emitting display BUNDESDRUCKEREI GMBH (DE) 2015-02-24 US claimed
EP-2471341-A1 DEVICE COMPRISING AN ORGANIC LIGHT EMITTING DISPLAY Bundesdruckerei GmbH (DE) 2012-07-04 EP claimed
US-20120146489-A1 DEVICE COMPRISING AN ORGANIC LIGHT EMITTING DISPLAY SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-06-14 US claimed
WO-2011023397-A1 DEVICE COMPRISING AN ORGANIC LIGHT EMITTING DISPLAY BUNDESDRUCKREI GMBH (DE) 2011-03-03 WO claimed
US-20080073815-A1 Vulcanizable composition based on ethylene-vinyl acetate copolymers, preparation thereof and use for production of products with elastomeric properties LANXESS DEUTSCHLAND GMBH (DE) 2008-03-27 US claimed
EP-1894947-A1 Vulcanisable compound based on ethylene-vinyl acetate copolymers, their manufacture and use in the manufacture of articles with rubber elastomer characteristics Lanxess Deutschland GmbH (DE) 2008-03-05 EP claimed
US-12636235-B2 Curable composition for dental impression DENTSPLY SIRONA INC. (US) 2026-05-26 US disclosed
US-12589056-B2 Curable composition for dental impression DENTSPLY SIRONA INC. (US) 2026-03-31 US disclosed
US-12492314-B2 Conductive composite film DDP SPECIALTY ELECTRONIC MATERIALS US 9, LLC (US) 2025-12-09 US disclosed
US-20250293221-A1 ELECTRONIC DEVICE ADVANCED SEMICONDUCTOR ENGINEERING, INC. (TW) 2025-09-18 US disclosed
US-12345171-B2 Protective coatings for aircraft engine components GE AVIO S.R.L. (IT) 2025-07-01 US disclosed
CN-118299471-A Preparation method of back P-I-N structure and preparation method of efficient crystalline silicon battery 常州时创能源股份有限公司 2024-07-05 CN disclosed
US-20240218193-A1 CONDUCTIVE COMPOSITE FILM DDP SPECIALTY ELECTRONIC MATERIALS US9, LLC 2024-07-04 US disclosed
US-6018011-A OBTAINED BY REACTING A POLYORGANOSILOXANE, WITH A REACTION PRODUCT OF AN ORGANOSILANE OF GIVEN FORMULA AND N-1-((METHYLDIETHOXYSILOXY)DIETHOXYSILYL)ETHYL-2-PYRROLIDONE; USE IN ALKOXY-CROSSLINKING RTV SILICONE RUBBER MIXTURES HUELS SILICONE GMBH (DE) 2000-01-25 US disclosed
US-6001948-A BASED ON HYDROXY-TERMINATED POLYDIORGANOSILOXANES CONTAINING A TRIALKOXYSILANE WITH A SUBSTITUTED AMIDOALKYL RADICAL, WHICH CAN BE PREPARED USING CONVENTIONAL MIXING TECHNOLOGIES. WACKER-CHEMIE GMBH (DE) 1999-12-14 US disclosed
EP-0712901-B1 Flame retardant polycarbonate moulding compositions BAYER AG (DE) 1999-03-10 EP disclosed
EP-0885931-A2 One-component alkoxy group containing RTV-systems Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) 1998-12-23 EP disclosed
EP-0885933-A1 One-component alkoxy containing RTV-silicone rubber compositions Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) 1998-12-23 EP disclosed
EP-0885915-A2 Polyorganosiloxanes having dialkoxyorganosiloxy groups Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) 1998-12-23 EP disclosed
EP-0712901-A2 Flame retardant polycarbonate moulding compositions BAYER AG (DE) 1996-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636235-B2 Curable composition for dental impression SMCHD1, CFH, H1-0 TSHR 3629/4885CYP3A4 2914/4885MEN1 2526/4885
US-12589056-B2 Curable composition for dental impression RER1, H1-0, CCT4 TSHR 2386/4885CYP3A4 4451/4885MEN1 2078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.