Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5076643 | 0.88 | ALDH1A1 (0.62) | KMT2AHPGDAKR1C3ALDH1A1MEN1 | |
| SCHEMBL148141 | 0.82 | PRNP (0.65) | PRNPKMT2AHPGDAKR1C3ALDH1A1 | |
| SCHEMBL717723 | 0.81 | AKR1C3 (0.64) | PRNPAKR1C3ALDH1A1MAPTPOLB | |
| SCHEMBL6918056 | 0.80 | PRNP (0.62) | PRNPKMT2AHPGDAKR1C3ALDH1A1 | |
| SCHEMBL6907969 | 0.80 | PRNP (0.62) | PRNPKMT2AHPGDAKR1C3ALDH1A1 | |
| SCHEMBL6914553 | 0.80 | PRNP (0.62) | PRNPKMT2AHPGDAKR1C3ALDH1A1 | |
| SCHEMBL6914492 | 0.80 | PRNP (0.62) | PRNPKMT2AHPGDAKR1C3ALDH1A1 | |
| SCHEMBL6914495 | 0.80 | PRNP (0.62) | PRNPKMT2AHPGDAKR1C3ALDH1A1 | |
| SCHEMBL6916057 | 0.80 | PRNP (0.62) | PRNPKMT2AHPGDAKR1C3ALDH1A1 | |
| SCHEMBL6915685 | 0.80 | PRNP (0.62) | PRNPKMT2AHPGDAKR1C3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448831-B | Process for preparing 4-acetyl-1-naphthoic acid | 北京元延医药科技股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115448831-A | Process for preparing 4-acetyl-1-naphthoic acid | 北京元延医药科技股份有限公司 | 2022-12-09 | — | — | CN | disclosed |
| US-20220158101-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-05-19 | — | — | US | disclosed |
| US-20220109116-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-04-07 | — | — | US | disclosed |
| WO-2020127176-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020127259-A2 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |
| US-20150357575-A1 | AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2015-12-10 | — | — | US | disclosed |
| US-20150357575-A1 | AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2015-12-10 | — | — | US | disclosed |
| US-8481733-B2 | Substituted imidazopyr- and imidazotri-azines | OSI Pharmaceuticals, LLC (US) | 2013-07-09 | — | — | US | disclosed |
| EP-2283020-B1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI PHARM INC (US) | 2012-10-31 | — | — | EP | disclosed |
| EP-2283020-A1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI Pharmaceuticals, Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009143051-A1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |
| US-20090286768-A1 | SUBSTITUTED IMIDAZOPYR- AND IMIDAZOTRI-AZINES | OSI PHARMACEUTICALS, INC. (US) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220109116-A1 | MATERIALS FOR ELECTRONIC DEVICES | EED, EPHA6, ERCC1 | PRNP 949/4885KMT2A 1528/4885HPGD 926/4885 |
| US-20090286768-A1 | SUBSTITUTED IMIDAZOPYR- AND IMIDAZOTRI-AZINES | ABL1, TPMT, CYP2C19 | PRNP 200/4885KMT2A 1103/4885HPGD 1283/4885 |
| US-20220158101-A1 | MATERIALS FOR ELECTRONIC DEVICES | EED, EPHA6, ERCC1 | PRNP 949/4885KMT2A 1528/4885HPGD 926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.