SCHEMBL5076643

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL717723	0.93	AKR1C3 (0.64)	ALDH1A1AKR1C3MAPTGAAHTR6
	SCHEMBL7915213	0.89	GAA (0.56)	ALDH1A1AKR1C3MAPTGAAKMT2A
	SCHEMBL1129191	0.88	PRNP (0.59)	ALDH1A1AKR1C3MAPTGAAKMT2A
	SCHEMBL11345028	0.88	AKR1C3 (0.48)	ALDH1A1AKR1C3MAPTGAAKMT2A
	SCHEMBL12748835	0.88	CYP1A2 (0.50)	ALDH1A1AKR1C3MAPTKMT2AKDM4E
	SCHEMBL28723825	0.83	AKR1C3 (0.53)	ALDH1A1AKR1C3MAPTGAAKMT2A
	SCHEMBL11054917	0.83	AKR1C3 (0.53)	ALDH1A1AKR1C3MAPTGAAKMT2A
	SCHEMBL16863997	0.83	MAPT (0.48)	ALDH1A1AKR1C3MAPTGAAKMT2A
	SCHEMBL6250609	0.83	MAPT (0.77)	ALDH1A1MAPTGAAKMT2AKDM4E
	SCHEMBL29522736	0.82	CDC25B (0.69)	ALDH1A1AKR1C3MAPTGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.