Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 12/20 | 0.43 |
| ▸ | CA1 | P00915 | 10/20 | 0.43 |
| ▸ | CA9 | Q16790 | 8/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6114656 | 0.98 | FAAH (0.50) | FAAHCA2CA1CA9PRKCA | |
| SCHEMBL10964774 | 0.98 | FAAH (0.50) | FAAHCA2CA1CA9PRKCA | |
| SCHEMBL6115103 | 0.92 | CA1 (0.41) | FAAHCA2CA1CA9PRKCA | |
| SCHEMBL8817616 | 0.85 | FAAH (0.46) | FAAHCA2CA1CA9PRKCA | |
| SCHEMBL25215798 | 0.83 | FAAH (0.50) | FAAHCA2CA1CA9PRKCA | |
| SCHEMBL6438694 | 0.83 | FAAH (0.50) | FAAHCA2CA1CA9PRKCA | |
| SCHEMBL6204495 | 0.83 | CA2 (0.54) | FAAHCA2CA1CA9PRKCA | |
| SCHEMBL2374982 | 0.83 | FAAH (0.50) | FAAHCA2CA1CA9PRKCA | |
| SCHEMBL2383575 | 0.83 | CA2 (0.46) | FAAHCA2CA1CA9PRKCA | |
| SCHEMBL3802854 | 0.83 | CA2 (0.58) | FAAHCA2CA1CA9PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4419284-A | Preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide | PFIZER INC. (US) | 1983-12-06 | — | — | US | disclosed |
| EP-0061315-A1 | Process for preparing penicillanic acid 1,1-dioxide derivatives and certain intermediates useful therein | PFIZER INC. (US) | 1982-09-29 | — | — | EP | disclosed |