Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | PRNP | P04156 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18622324 | 0.77 | MAP3K5 (0.44) | RAB9ATP53KDM4EPRNPRXFP1 | |
| SCHEMBL29427872 | 0.75 | MGAM (0.50) | RAB9AKDM4EMGAMMAP3K5ALDH1A1 | |
| SCHEMBL5350724 | 0.75 | MGAM (0.42) | RAB9ATP53KDM4ECYP1A2CCKAR | |
| SCHEMBL2337793 | 0.75 | MGAM (0.50) | RAB9AKDM4EMGAMMAP3K5ALDH1A1 | |
| SCHEMBL27288452 | 0.75 | NPC1 (0.49) | RAB9AGAAALDH1A1MAPTKMT2A | |
| SCHEMBL29668334 | 0.74 | IKBKB (0.47) | RAB9ATP53KDM4ECYP1A2CCKAR | |
| SCHEMBL31325746 | 0.74 | MAP3K5 (0.46) | TP53KDM4ECYP1A2MGAMMAP3K5 | |
| SCHEMBL16506805 | 0.74 | RAB9A (0.41) | RAB9ATP53KDM4ECYP1A2CCKAR | |
| SCHEMBL2005662 | 0.74 | MGAM (0.41) | RAB9ATP53KDM4ECYP1A2CCKAR | |
| SCHEMBL422040 | 0.74 | IKBKB (0.47) | RAB9ATP53KDM4ECYP1A2CCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004389-B1 | 4-AMINO-6,7-DIMETHOXY QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AND A PHARMACEUTICAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-04-07 | — | — | EP | disclosed |