Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.74 |
| ▸ | RECQL | P46063 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9187561 | 0.86 | NPC1 (1.00) | NPC1RAB9ARECQLKDM4EPOLB | |
| SCHEMBL9642715 | 0.84 | NPC1 (0.89) | NPC1RAB9ARECQLKDM4EPOLB | |
| SCHEMBL13230076 | 0.84 | NPC1 (0.75) | NPC1RAB9ARECQLKDM4EPOLB | |
| SCHEMBL4935994 | 0.83 | NPC1 (0.51) | NPC1RAB9ARECQLKDM4ECYP11B1 | |
| SCHEMBL2305236 | 0.83 | NPC1 (0.68) | NPC1RAB9ARECQLKDM4EPOLB | |
| SCHEMBL30015078 | 0.83 | NPC1 (0.68) | NPC1RAB9ARECQLKDM4EPOLB | |
| SCHEMBL13812975 | 0.82 | S1PR4 (0.55) | NPC1RAB9ARECQLKDM4ECYP11B1 | |
| SCHEMBL18585107 | 0.82 | CYP11B1 (0.64) | NPC1RAB9ARECQLKDM4ECYP11B1 | |
| SCHEMBL10779649 | 0.81 | NPC1 (0.83) | NPC1RAB9ARECQLKDM4EPOLB | |
| SCHEMBL13435257 | 0.81 | NPC1 (0.89) | NPC1RAB9ARECQLKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346242-A | Method for preparing substituted meta-phenylalkoxynitrobenzenes | AMERICAN CYANAMID COMPANY (US) | 1982-08-24 | — | — | US | disclosed |