Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 2/20 | 0.55 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4879420 | 0.86 | POLB (0.57) | S1PR4PIN1FAAHBCHEACHE | |
| SCHEMBL11292192 | 0.82 | NPC1 (0.74) | PIN1CYP11B1CYP11B2NPC1RAB9A | |
| SCHEMBL15243653 | 0.81 | MRGPRX4 (0.53) | S1PR4NPC1RAB9AFAAHBCHE | |
| SCHEMBL363493 | 0.80 | S1PR4 (0.64) | S1PR4NPC1RAB9ARECQLHTR2C | |
| SCHEMBL7957556 | 0.80 | S1PR4 (0.60) | S1PR4NPC1RAB9ARECQLKDM4E | |
| SCHEMBL2798909 | 0.78 | S1PR4 (0.59) | S1PR4NPC1RAB9ARECQLKDM4E | |
| SCHEMBL19174959 | 0.78 | S1PR4 (0.67) | S1PR4NPC1RAB9ARECQLHTR2C | |
| SCHEMBL29684617 | 0.78 | S1PR4 (0.67) | S1PR4NPC1RAB9ARECQLHTR2C | |
| SCHEMBL357386 | 0.78 | S1PR4 (0.59) | S1PR4NPC1RAB9ARECQLKDM4E | |
| SCHEMBL13812882 | 0.78 | G6PD (0.58) | NPC1RAB9AFAAHBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |