Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12809903 | 0.70 | — | — | |
| SCHEMBL31310506 | 0.70 | — | — | |
| SCHEMBL14868792 | 0.69 | — | — | |
| SCHEMBL9843335 | 0.67 | ALDH1A1 (0.39) | CYP1A2TOP2AMEN1CYP3A4TSHR | |
| SCHEMBL31619938 | 0.67 | ALDH1A1 (0.37) | TOP2AMEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL15359895 | 0.64 | — | — | |
| SCHEMBL27295267 | 0.61 | KAT2B (0.34) | CYP1A2KAT2BBRD9USP2MEN1 | |
| SCHEMBL11489827 | 0.60 | KDM4E (0.33) | KAT2BBRD9ALDH1A1 | |
| SCHEMBL10501374 | 0.60 | GAA (0.38) | MAPK1KMT2A | |
| SCHEMBL14868745 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015452-B1 | 6-SUBSTITUTED-3-DIMETHYLAMINO-4-METHYL-1,2,4-TRIAZIN-5-(4H)-ONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1982-01-20 | — | — | EP | claimed |
| EP-0015452-A1 | 6-Substituted-3-dimethylamino-4-methyl-1,2,4-triazin-5-(4H)-ones, processes for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-17 | — | — | EP | disclosed |