Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12809903 | 0.70 | — | — | |
| SCHEMBL31310506 | 0.70 | — | — | |
| SCHEMBL31619938 | 0.67 | ALDH1A1 (0.37) | ALDH1A1HPGDHSD17B10TOP2AMEN1 | |
| SCHEMBL11479664 | 0.60 | ALDH1A1 (0.35) | ALDH1A1CYP1A2HPGDCASP1CASP7 | |
| SCHEMBL10717482 | 0.60 | CA12 (0.33) | ALDH1A1CYP1A2HPGDHSD17B10CYP2D6 | |
| SCHEMBL3524163 | 0.57 | POLB (0.33) | ALDH1A1CYP1A2HPGDCYP2D6MEN1 | |
| SCHEMBL10040901 | 0.56 | — | — | |
| SCHEMBL18961662 | 0.54 | BRD9 (0.40) | ALDH1A1 | |
| SCHEMBL22415810 | 0.54 | CNR2 (0.47) | ALDH1A1CYP1A2HPGDCASP1CASP7 | |
| SCHEMBL23164949 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458111-A1 | 1,6-dihydro-3-dimethylamino-4-methyl-1,2,4-triazine derivatives | BAYER AG (DE) | 1991-11-27 | — | — | EP | claimed |
| US-4447258-A | 3-Dimethylamino-4-methyl-1,2,4-triazin-5(4H)-ones and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1984-05-08 | — | — | US | claimed |
| EP-0015452-B1 | 6-SUBSTITUTED-3-DIMETHYLAMINO-4-METHYL-1,2,4-TRIAZIN-5-(4H)-ONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1982-01-20 | — | — | EP | claimed |
| EP-0015452-A1 | 6-Substituted-3-dimethylamino-4-methyl-1,2,4-triazin-5-(4H)-ones, processes for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-17 | — | — | EP | claimed |
| EP-0458111-A1 | 1,6-dihydro-3-dimethylamino-4-methyl-1,2,4-triazine derivatives | BAYER AG (DE) | 1991-11-27 | — | — | EP | disclosed |
| US-4447258-A | 3-Dimethylamino-4-methyl-1,2,4-triazin-5(4H)-ones and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1984-05-08 | — | — | US | disclosed |
| US-4447258-A | 3-Dimethylamino-4-methyl-1,2,4-triazin-5(4H)-ones and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1984-05-08 | — | — | US | disclosed |
| EP-0015452-B1 | 6-SUBSTITUTED-3-DIMETHYLAMINO-4-METHYL-1,2,4-TRIAZIN-5-(4H)-ONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1982-01-20 | — | — | EP | disclosed |
| EP-0015452-B1 | 6-SUBSTITUTED-3-DIMETHYLAMINO-4-METHYL-1,2,4-TRIAZIN-5-(4H)-ONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1982-01-20 | — | — | EP | disclosed |
| EP-0015452-A1 | 6-Substituted-3-dimethylamino-4-methyl-1,2,4-triazin-5-(4H)-ones, processes for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-17 | — | — | EP | disclosed |
| EP-0015452-A1 | 6-Substituted-3-dimethylamino-4-methyl-1,2,4-triazin-5-(4H)-ones, processes for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-17 | — | — | EP | disclosed |