Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288778 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KMT2ARAB9ASMN1; SMN2PKM | |
| SCHEMBL11291463 | 0.98 | ALDH1A1 (0.41) | ALDH1A1KMT2ARAB9ASMN1; SMN2PKM | |
| SCHEMBL11353342 | 0.90 | ALDH1A1 (0.43) | ALDH1A1KMT2ARAB9ASMN1; SMN2PKM | |
| SCHEMBL11246208 | 0.88 | PKM (0.40) | ALDH1A1KMT2ARAB9ASMN1; SMN2PKM | |
| SCHEMBL11243582 | 0.88 | PKM (0.40) | ALDH1A1KMT2ARAB9ASMN1; SMN2PKM | |
| SCHEMBL11359679 | 0.87 | ALDH1A1 (0.41) | ALDH1A1KMT2ARAB9ASMN1; SMN2PKM | |
| SCHEMBL11253803 | 0.86 | PKM (0.38) | ALDH1A1KMT2ARAB9ASMN1; SMN2PKM | |
| SCHEMBL11276019 | 0.85 | ALDH1A1 (0.40) | ALDH1A1KMT2ARAB9ASMN1; SMN2PKM | |
| SCHEMBL11276466 | 0.85 | ALDH1A1 (0.40) | ALDH1A1KMT2ARAB9ASMN1; SMN2PKM | |
| SCHEMBL11292926 | 0.83 | HPGD (0.41) | ALDH1A1KMT2ARAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311647-A | Process for preparation of (hydrocarbonthio)oxamides | THE B. F. GOODRICH COMPANY (US) | 1982-01-19 | — | — | US | disclosed |