Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.42 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048379 | 0.88 | AGTR2 (0.50) | POLBFKBP1AHTR2C | |
| SCHEMBL11048376 | 0.88 | AGTR2 (0.50) | POLBFKBP1AHTR2C | |
| SCHEMBL7423869 | 0.84 | POLB (0.51) | POLBFKBP1ATSHRL3MBTL1KDM4E | |
| SCHEMBL7310404 | 0.83 | POLB (0.62) | POLBFKBP1ATSHRL3MBTL1KDM4E | |
| SCHEMBL8477557 | 0.83 | POLB (0.62) | POLBFKBP1ATSHRL3MBTL1KDM4E | |
| SCHEMBL8477698 | 0.83 | POLB (0.62) | POLBFKBP1ATSHRL3MBTL1KDM4E | |
| SCHEMBL8482480 | 0.83 | POLB (0.62) | POLBFKBP1ATSHRL3MBTL1KDM4E | |
| SCHEMBL8477697 | 0.83 | POLB (0.62) | POLBFKBP1ATSHRL3MBTL1KDM4E | |
| SCHEMBL16356837 | 0.83 | POLB (0.52) | POLBFKBP1ATSHRL3MBTL1KDM4E | |
| SCHEMBL8477564 | 0.83 | POLB (0.62) | POLBFKBP1ATSHRL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052991-A1 | Carboxyalkyl amino acid derivatives of various substituted prolines | E.R. Squibb & Sons, Inc. (US) | 1982-06-02 | — | — | EP | disclosed |