Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11125534 | 0.91 | ESR2 (0.37) | KDM4EBACE1ENPP2NR1H3HDAC2 | |
| SCHEMBL3976672 | 0.85 | GRIN2D (0.40) | BACE1HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL31330770 | 0.85 | GRIN2D (0.40) | BACE1HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL4370207 | 0.85 | GRIN2D (0.40) | BACE1HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL9251224 | 0.84 | FLT3 (0.41) | BACE1HDAC3HDAC1HDAC8NCOR2 | |
| SCHEMBL9251227 | 0.84 | FLT3 (0.41) | BACE1HDAC3HDAC1HDAC8NCOR2 | |
| SCHEMBL7931796 | 0.83 | HPGD (0.38) | KDM4ENFE2L2 | |
| SCHEMBL29203723 | 0.83 | ESR2 (0.51) | BACE1ESR2ESR1PTGER1PTGER3 | |
| SCHEMBL28285681 | 0.83 | ESR2 (0.51) | BACE1ESR2ESR1PTGER1PTGER3 | |
| SCHEMBL7931798 | 0.83 | HPGD (0.38) | KDM4ENFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023028-B1 | MIXTURES OF OPTICAL BRIGHTENERS AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-12-15 | — | — | EP | disclosed |