Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931798 | 1.00 | HPGD (0.38) | HPGDMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL11125534 | 0.91 | ESR2 (0.37) | KDM4E | |
| SCHEMBL4370207 | 0.85 | GRIN2D (0.40) | HPGDALDH1A1MAPK1HSD17B10 | |
| SCHEMBL31330770 | 0.85 | GRIN2D (0.40) | HPGDALDH1A1MAPK1HSD17B10 | |
| SCHEMBL3976672 | 0.85 | GRIN2D (0.40) | HPGDALDH1A1MAPK1HSD17B10 | |
| SCHEMBL9251224 | 0.84 | FLT3 (0.41) | HPGDALDH1A1MAPK1HSD17B10 | |
| SCHEMBL9251227 | 0.84 | FLT3 (0.41) | HPGDALDH1A1MAPK1HSD17B10 | |
| SCHEMBL11293055 | 0.83 | KDM4E (0.43) | KDM4ENFE2L2 | |
| SCHEMBL29203723 | 0.83 | ESR2 (0.51) | MEN1KMT2AADORA1NFE2L2 | |
| SCHEMBL28285681 | 0.83 | ESR2 (0.51) | MEN1KMT2AADORA1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879814-B1 | Triaromatic compounds, compositions containing them and uses thereof | CT INTERNAT DE BR RECH S DERMA (FR) | 2001-11-28 | — | — | EP | disclosed |