Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16352164 | 0.82 | MEN1 (0.34) | CYP1A2MEN1KMT2ATSHRLMNA | |
| SCHEMBL9773402 | 0.77 | TSHR (0.37) | CYP1A2MEN1KMT2ATSHRPPARD | |
| SCHEMBL28927204 | 0.77 | MEN1 (0.32) | CYP1A2MEN1KMT2A | |
| SCHEMBL28450083 | 0.77 | ALDH1A1 (0.55) | CYP1A2MEN1KMT2ASMPD1ALDH1A1 | |
| SCHEMBL28450084 | 0.75 | SAT1 (0.41) | CYP1A2MEN1KMT2ATSHRPPARD | |
| SCHEMBL1527287 | 0.75 | — | — | |
| SCHEMBL4419686 | 0.75 | — | — | |
| SCHEMBL31503116 | 0.74 | MEN1 (0.32) | CYP1A2MEN1KMT2ATSHRPPARD | |
| SCHEMBL5918893 | 0.74 | PPARD (0.50) | CYP1A2MEN1KMT2ATSHRPPARD | |
| Ammonia Solution, Strong SCHEMBL9019349 | 0.73 | ALDH1A1 (0.56) | CYP1A2GABBR2TSHRTHPOGABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009022-B1 | PROCESSES FOR PREPARING D,L-2-AMINO-4((HYDROXY)(METHYL)PHOSPHINOYL)-BUTYRIC ACID AND AN ACETAL OF AN ESTER OF 3-OXOPROPYLMETHYL PHOSPHINIC ACID | MEIJI SEIKA KAISHA LTD. (JP) | 1982-07-07 | — | — | EP | disclosed |
| US-4264532-A | REACTING A DIALKYL PHOSPHONITE WITH ACROLEIN; ESTERIFING AND THEN REACTING WITH POTASSIUM CYANIDE AND AMMONIUM CHLORIDE | MEIJI SEIKA KAISHA LTD. (JP) | 1981-04-28 | — | — | US | disclosed |
| EP-0009022-A1 | Processes for preparing D,L-2-amino-4((hydroxy)(methyl)phosphinoyl)-butyric acid and an acetal of an ester of 3-oxopropylmethyl phosphinic acid | MEIJI SEIKA KAISHA LTD. (JP) | 1980-03-19 | — | — | EP | disclosed |