SCHEMBL11293443

SCHEMBL11293443

Oc1ccc(/N=N/C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.59
KMT2A Q03164 6/20 0.59
NPC1 O15118 3/20 0.59
ESR1 P03372 3/20 0.45
ESR2 Q92731 3/20 0.45
ALDH1A1 P00352 3/20 0.45
CYP3A4 P08684 1/20 0.45
HSP90AA1 P07900 4/20 0.44
RAB9A P51151 2/20 0.44
IDE P14735 1/20 0.43
GLB1 P16278 1/20 0.42
CTRB1 P17538 1/20 0.42
CTRC Q99895 1/20 0.42
MAPT P10636 5/20 0.39
TDP1 Q9NUW8 3/20 0.39
LMNA P02545 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11293444 1.00 MEN1 (0.59) MEN1KMT2ANPC1ESR1ESR2
SCHEMBL491313 0.85 ALDH1A1 (0.52) MEN1KMT2ANPC1ALDH1A1HSP90AA1
SCHEMBL491314 0.85 ALDH1A1 (0.52) MEN1KMT2ANPC1ALDH1A1HSP90AA1
SCHEMBL11293876 0.80 TSHR (0.39) MEN1KMT2ANPC1ALDH1A1CYP3A4
SCHEMBL11298591 0.80 MEN1 (0.47) MEN1KMT2ANPC1ALDH1A1RAB9A
SCHEMBL11298593 0.80 MEN1 (0.47) MEN1KMT2ANPC1ALDH1A1RAB9A
SCHEMBL16738045 0.79 TRPA1 (0.63) MEN1KMT2ANPC1ALDH1A1RAB9A
SCHEMBL16738046 0.79 TRPA1 (0.63) MEN1KMT2ANPC1ALDH1A1RAB9A
Hydrochloric Acid SCHEMBL16737812 0.78 TRPA1 (0.61) MEN1KMT2ANPC1ALDH1A1RAB9A
SCHEMBL16737809 0.77 TRPA1 (0.46) MEN1KMT2ANPC1ALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11865374-B2 Functionalized polymers EVONIK OPERATIONS GMBH (DE) 2024-01-09 US claimed
US-20230312791-A1 FUNCTIONALIZED POLYMERS EVONIK OPERATIONS GMBH (DE) 2023-10-05 US claimed
EP-4200343-A1 FUNCTIONALIZED POLYMERS Evonik Operations GmbH (DE) 2023-06-28 EP claimed
CN-116096764-A Functionalized polymers 赢创运营有限公司 2023-05-09 CN claimed
CN-111356710-B Functionalized polymers 赢创运营有限公司 2022-04-26 CN claimed
WO-2022038054-A1 FUNCTIONALIZED POLYMERS EVONIK OPERATIONS GMBH (DE) 2022-02-24 WO claimed
EP-3957659-A1 FUNCTIONALIZED POLYMERS Evonik Operations GmbH (DE) 2022-02-23 EP claimed
EP-3710503-B1 FUNCTIONALIZED POLYMERS EVONIK OPERATIONS GMBH (DE) 2022-01-05 EP claimed
US-20200383896-A1 FUNCTIONALIZED POLYMERS EVONIK OPERATIONS GMBH (DE) 2020-12-10 US claimed
EP-3710503-A1 FUNCTIONALIZED POLYMERS Evonik Degussa GmbH (DE) 2020-09-23 EP claimed
CN-111356710-A Functionalized polymers 赢创运营有限公司 2020-06-30 CN claimed
US-11865374-B2 Functionalized polymers EVONIK OPERATIONS GMBH (DE) 2024-01-09 US disclosed
US-20230312791-A1 FUNCTIONALIZED POLYMERS EVONIK OPERATIONS GMBH (DE) 2023-10-05 US disclosed
EP-4200343-A1 FUNCTIONALIZED POLYMERS Evonik Operations GmbH (DE) 2023-06-28 EP disclosed
CN-116096764-A Functionalized polymers 赢创运营有限公司 2023-05-09 CN disclosed
EP-0005296-B1 PROCESS FOR THE MANUFACTURE OF DICHLOROMETHANE SOLVAY & Cie (Société Anonyme) (BE) 1982-01-06 EP disclosed
EP-0005296-A1 Process for the manufacture of dichloromethane SOLVAY & Cie (Société Anonyme) (BE) 1979-11-14 EP disclosed
US-4066524-A IMIDAZOLE POLYMERS AND PREPARATION THEREOF WITH RADIATION AND CHEMICAL INITIATOR HERCULES INCORPORATED (US) 1978-01-03 US disclosed
US-3970612-A BULK POLYMERIZATION HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-07-20 US disclosed
US-3948740-A Polymerization of water soluble monomers with radiation and chemical initiator HERCULES INCORPORATED (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11865374-B2 Functionalized polymers PUF60, PARN, PARG MEN1 4016/4885KMT2A 2539/4885NPC1 4460/4885
US-20200383896-A1 FUNCTIONALIZED POLYMERS PUF60, PARN, PARG MEN1 4016/4885KMT2A 2539/4885NPC1 4460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.