SCHEMBL1129359

SCHEMBL1129359

O=C(O)c1cccc(C(c2ccccc2)c2ccccc2)c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.64
KMT2A Q03164 2/20 0.64
GAA P10253 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
HNF4A P41235 1/20 0.50
KDM4E B2RXH2 3/20 0.48
HPGD P15428 2/20 0.48
ALB P02768 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MMP2 P08253 1/20 0.48
ALOX15 P16050 1/20 0.46
HMGB1 P09429 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11474084 0.98 ALDH1A1 (0.62) ALDH1A1KMT2AGAATDP1HNF4A
Zinc Ion SCHEMBL11474080 0.84 ALDH1A1 (0.50) ALDH1A1KMT2AGAATDP1HNF4A
SCHEMBL8945914 0.84 ALDH1A1 (0.79) ALDH1A1KMT2AGAATDP1KDM4E
SCHEMBL31336042 0.82 ALB (0.59) ALDH1A1KMT2AGAATDP1HNF4A
SCHEMBL312797 0.82 ALDH1A1 (0.50) ALDH1A1KMT2AGAATDP1HNF4A
SCHEMBL9769911 0.81 ALDH1A1 (0.49) ALDH1A1KMT2AGAATDP1HNF4A
SCHEMBL1858272 0.81 ALDH1A1 (0.49) ALDH1A1KMT2AGAATDP1HNF4A
SCHEMBL5888693 0.80 ALDH1A1 (0.49) ALDH1A1KMT2AGAATDP1HNF4A
SCHEMBL28692019 0.78 ALDH1A1 (0.44) ALDH1A1KMT2AGAATDP1HNF4A
SCHEMBL438546 0.78 ALDH1A1 (1.00) ALDH1A1KMT2AGAATDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9309803-A None JP disclosed
US-8283287-B2 Thermosensitive recording material RICOH COMPANY, LTD. (JP) 2012-10-09 US disclosed
EP-2036737-B1 Thermosensitive recording material RICOH CO LTD (JP) 2011-02-16 EP disclosed
US-20090075817-A1 THERMOSENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2009-03-19 US disclosed
EP-2036737-A1 Thermosensitive recording material Ricoh Company, Ltd. (JP) 2009-03-18 EP disclosed
JP-H09309803-A GERMICIDAL AND FUNGICIDAL ANENT MITSUI PETROCHEM IND LTD 1997-12-02 JP disclosed
EP-0482668-B1 HEAT SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1993-08-04 EP disclosed
US-5187143-A Thermographic mixture of basic leuco dye and color developer comprising a zinc salt of terephthaldehydic acid or a composite salt also containing an aromatic acid KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-02-16 US disclosed
EP-0482668-A1 Heat sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-04-29 EP disclosed
US-4920091-A CONTAINING SALICYLIC ACID DERIVATIVE AS ELECTRON ACCEPTING COLOR DEVELOPER; STABLE IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1990-04-24 US disclosed
US-4918047-A CONTAINING OXYSALICYLIC ACID DERIVATIVE AND ZINC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
EP-0253666-A2 Heat-sensitive recording material containing dye-forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed
US-4219219-A Developers for pressure-sensitive recording and developing sheets containing them FUJI PHOTO FILM CO., LTD. (JP) 1980-08-26 US disclosed