Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | BRD2 | P25440 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpyrrolidone SCHEMBL8623150 | 0.92 | BRD4 (0.68) | BRD4BRD2KMT2ALMNAALDH1A1 | |
| Methylpyrrolidone SCHEMBL180327 | 0.92 | BRD4 (0.68) | BRD4BRD2KMT2ALMNAALDH1A1 | |
| SCHEMBL9309624 | 0.89 | BRD4 (0.57) | BRD4BRD2SMN1; SMN2MITFACHE | |
| Methylpyrrolidone SCHEMBL10422809 | 0.84 | BRD4 (0.57) | BRD4BRD2SMN1; SMN2KMT2ALMNA | |
| SCHEMBL6886758 | 0.84 | BRD4 (0.80) | BRD4BRD2SMN1; SMN2MITFACHE | |
| SCHEMBL14747422 | 0.84 | BRD4 (0.80) | BRD4BRD2SMN1; SMN2MITFACHE | |
| SCHEMBL1626056 | 0.84 | BRD4 (0.80) | BRD4BRD2SMN1; SMN2MITFACHE | |
| SCHEMBL54926 | 0.84 | — | — | |
| SCHEMBL6885804 | 0.84 | BRD4 (0.80) | BRD4BRD2SMN1; SMN2MITFACHE | |
| SCHEMBL329328 | 0.84 | BRD4 (0.80) | BRD4BRD2SMN1; SMN2MITFACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054426-A2 | Improvements in or relating to siloxanes | M & T CHEMICALS, INC. (US) | 1982-06-23 | — | — | EP | disclosed |