Methylpyrrolidone

Methylpyrrolidone

SCHEMBL180327

CC(=O)N(C)C.CN1CCCC1=O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.68
BRD2 P25440 1/20 0.68
LMNA P02545 2/20 0.38
KMT2A Q03164 3/20 0.37
TSHR P16473 2/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA13 Q8N1Q1 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
INMT O95050 2/20 0.35
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylpyrrolidone SCHEMBL8623150 1.00 BRD4 (0.68) BRD4BRD2LMNAKMT2ATSHR
SCHEMBL11294331 0.92 BRD4 (0.57) BRD4BRD2LMNAKMT2AALDH1A1
Methylpyrrolidone SCHEMBL10422809 0.91 BRD4 (0.57) BRD4BRD2LMNAKMT2ATSHR
Methylpyrrolidone SCHEMBL8925669 0.88 BRD4 (0.68) BRD4BRD2LMNAKMT2ATSHR
Methylpyrrolidone SCHEMBL2243830 0.87 BRD4 (0.81) BRD4BRD2LMNAKMT2ATSHR
Methylpyrrolidone SCHEMBL1801243 0.85 BRD4 (0.77) BRD4BRD2LMNAKMT2ATSHR
Methylpyrrolidone SCHEMBL11078812 0.85 BRD4 (0.85) BRD4BRD2LMNAKMT2ATSHR
Methylpyrrolidone SCHEMBL10411702 0.84 BRD4 (0.49) BRD4BRD2TSHR
Methylpyrrolidone SCHEMBL28884394 0.83 BRD4 (0.74) BRD4BRD2LMNAKMT2ATSHR
Methylpyrrolidone SCHEMBL28608007 0.83 BRD4 (0.74) BRD4BRD2LMNAKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192585-A1 METHOD FOR PREPARING ACRYLIC ACID FROM BETA-PROPIOLACTONE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-06-22 US claimed
EP-4153556-A1 METHOD FOR PREPARING ACRYLIC ACID FROM BETA-PROPIOLACTONE Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2023-03-29 EP claimed
CN-113314746-B Cross-linked functionalized polyvinyl alcohol anion exchange membrane and preparation method thereof 温州黑鹰网络科技有限公司 2022-09-09 CN claimed
WO-2021233839-A1 METHOD FOR PREPARING ACRYLIC ACID FROM β-PROPIOLACTONE COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2021-11-25 WO claimed
CN-113314746-A Cross-linked functionalized polyvinyl alcohol anion exchange membrane and preparation method thereof 温州黑鹰网络科技有限公司 2021-08-27 CN claimed
WO-2015137914-A1 METHODS FOR PRODUCING NYLON 7 EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-09-17 WO claimed
US-8034893-B2 Resin resolution composition, polyimide resin, and semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-10-11 US claimed
US-20100291306-A1 Hydroxyalkylated Chitosan Solution DAINICHISEIKA COLOR & CHEMICALS MFG CO., LTD (JP) 2010-11-18 US claimed
US-5003103-A Decarboxylation, chlorodenitration, catalysis OCCIDENTAL CHEMICAL CORPORATION (US) 1991-03-26 US claimed
WO-2024132901-A1 MICROBIOCIDAL PYRIDAZINE DIHYDROOXADIAZINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 WO disclosed
WO-2024132895-A1 MICROBIOCIDAL DIHYDROOXADIAZINYL PYRIDAZINONE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 WO disclosed
US-20240182420-A1 MICROBIOCIDAL ISONICOTINIC AMIDE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-06 US disclosed
WO-2024089191-A1 MICROBIOCIDAL HETEROBICYCLIC DIHYDROOXADIAZINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-05-02 WO disclosed
CN-117545757-A 5-oxo-pyrido [2,3-d ] pyridazin-6 (5H) -ylacetamides 詹森药业有限公司 2024-02-09 CN disclosed
US-4598091-A (1,2-diphenyl)-ethylenediamine)-platinum (II) complex compounds DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-07-01 US disclosed
US-4539393-A Dimensionally stable poly-m-phenylene isophthalamide film TEIJIN LIMITED (JP) 1985-09-03 US disclosed
US-4413115-A CONTAINING UNITS FROM 1,2,3,4-TETRAMETHYL-CYCLOBUTANE-1,2,3,4-TETRACARBOXYLIC ACID STANDARD OIL COMPANY (INDIANA) (US) 1983-11-01 US disclosed
EP-0091778-A2 Improvement in or relating to aromatic polyamide film TEIJIN LIMITED (JP) 1983-10-19 EP disclosed
US-4145532-A TERTIARY AMINE OXIDE SOLVENT AKZONA INCORPORATED (US) 1979-03-20 US disclosed
US-4076694-A FROM A POLYISOCYANATE AND A SUBSTITUTED CYCLIC CARBOXYLIC ACID ANHYDRIDE BAYER AKTIENGESELLSCHAFT (DT) 1978-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192585-A1 METHOD FOR PREPARING ACRYLIC ACID FROM BETA-PROPIOLACTONE ALAD, PCCA, APEH BRD4 3916/4885BRD2 2699/4885LMNA 973/4885
US-20240182420-A1 MICROBIOCIDAL ISONICOTINIC AMIDE DERIVATIVES ARG2, MPO, ARG1 BRD4 3513/4885BRD2 3085/4885LMNA 4482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.