Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297133 | 0.84 | MTNR1A (0.51) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL11296292 | 0.82 | MAPT (0.65) | MAPTMEN1KMT2AKCNH2PTGS2 | |
| SCHEMBL7432149 | 0.81 | MAPT (0.55) | MAPTMEN1KMT2AKCNH2PTGS2 | |
| SCHEMBL11290045 | 0.80 | MAPT (0.72) | MAPTMEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL2889097 | 0.80 | MAPT (0.72) | MAPTMEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL11290364 | 0.80 | EPHX1 (0.44) | MAPTMEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL3657157 | 0.77 | MAPT (0.55) | MAPTMEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL11290903 | 0.75 | MAPT (0.53) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11289014 | 0.75 | MAPT (0.70) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11292673 | 0.74 | MAPT (0.65) | MAPTMEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |