Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11298272 | 0.87 | MAPT (0.66) | MTNR1AMTNR1BMAPTLMNAABCB11 | |
| SCHEMBL11294402 | 0.84 | MAPT (0.54) | MAPTLMNAABCB11MAPK1GAA | |
| SCHEMBL11265051 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL11289014 | 0.82 | MAPT (0.70) | MAPTLMNAABCB11MAPK1GAA | |
| SCHEMBL11290903 | 0.82 | MAPT (0.53) | MAPTLMNAABCB11MAPK1DRD3 | |
| SCHEMBL11292673 | 0.81 | MAPT (0.65) | MAPTLMNAABCB11MAPK1DRD3 | |
| SCHEMBL15258345 | 0.80 | ABCB11 (0.78) | MAPTLMNAABCB11MAPK1GAA | |
| SCHEMBL7431214 | 0.77 | MTNR1A (0.52) | MTNR1AMTNR1BMAPTLMNADRD3 | |
| SCHEMBL11293676 | 0.77 | ABCB11 (0.57) | MAPTLMNAABCB11MAPK1GAA | |
| SCHEMBL11292129 | 0.74 | LMNA (0.64) | MAPTLMNAABCB11MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |