SCHEMBL11294752

SCHEMBL11294752

C1=CC(=Cc2ccccc2)CC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
ALDH1A1 P00352 6/20 0.42
F3 P13726 1/20 0.41
HTT P42858 2/20 0.39
HPGD P15428 5/20 0.36
LMNA P02545 2/20 0.36
KDM4E B2RXH2 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAOB P27338 3/20 0.35
PIM1 P11309 1/20 0.34
PIM3 Q86V86 1/20 0.34
PIM2 Q9P1W9 1/20 0.34
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
MAPT P10636 3/20 0.33
TSHR P16473 1/20 0.33
MIF P14174 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL9007792 0.80 ALDH1A1 (0.45) CYP1A2ALDH1A1F3HTTHPGD
SCHEMBL28869856 0.74 ALDH1A1 (0.46) CYP1A2ALDH1A1F3HTTHPGD
SCHEMBL29281743 0.74 ALDH1A1 (0.46) CYP1A2ALDH1A1F3HTTHPGD
SCHEMBL31633218 0.72 CYP1A2 (0.48) CYP1A2ALDH1A1F3HTTHPGD
SCHEMBL28066368 0.70 CYP1A2 (0.44) CYP1A2ALDH1A1F3HTTHPGD
SCHEMBL2137795 0.70 ALDH1A1 (0.33) CYP1A2ALDH1A1F3HTTGAA
SCHEMBL6745371 0.70 ALDH1A1 (0.37) CYP1A2ALDH1A1F3HTTHPGD
SCHEMBL10632138 0.67 CYP1A2 (0.52) CYP1A2ALDH1A1F3HTTHPGD
SCHEMBL63597 0.67 CYP1A2 (0.52) CYP1A2ALDH1A1F3HTTHPGD
SCHEMBL28063664 0.67 CYP1A2 (0.38) CYP1A2ALDH1A1F3HTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0018894-B1 ESTERS OF ALLETHROLONE DERIVATIVES AND CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1982-02-17 EP disclosed
EP-0029617-A1 Use of tertiary heterocyclic amines as synergists in pesticides; derivatives of cycloamines C.F. Spiess & Sohn GmbH & Co. Chemische Fabrik (DE) 1981-06-03 EP disclosed
EP-0018894-A1 Esters of allethrolone derivatives and carboxylic acids, process for their preparation and the compositions containing them ROUSSEL-UCLAF (FR) 1980-11-12 EP disclosed