Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL28226585 | 0.96 | ALDH1A1 (0.35) | ALDH1A1HTTCYP1A2F3NFKB1 | |
| SCHEMBL28248584 | 0.89 | ALDH1A1 (0.35) | ALDH1A1HTTCYP1A2F3NFKB1 | |
| SCHEMBL21616789 | 0.80 | NPC1 (0.42) | HTTMAPTSMN1; SMN2MAOANPC1 | |
| SCHEMBL28182498 | 0.78 | PTPN1 (0.50) | ALDH1A1CYP1A2LMNAMAPTCYP2C19 | |
| SCHEMBL30849656 | 0.77 | CYP1A2 (0.44) | ALDH1A1CYP1A2RELALMNAMAPT | |
| SCHEMBL28308866 | 0.72 | CA1 (0.33) | CYP2D6CYP2C19 | |
| SCHEMBL28066368 | 0.72 | CYP1A2 (0.44) | ALDH1A1HTTCYP1A2F3LMNA | |
| SCHEMBL28175288 | 0.72 | CYP1A2 (0.34) | ALDH1A1HTTCYP1A2F3NFKB1 | |
| SCHEMBL8401484 | 0.71 | CYP1A2 (0.33) | ALDH1A1HTTCYP1A2F3PIM1 | |
| SCHEMBL1028440 | 0.71 | IKBKB (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110392725-A | Novel smooth orientation composition for pre-tilt angle in stabilizing solution crystal layer | 罗利克技术有限公司 | 2019-10-29 | — | — | CN | claimed |
| US-20030069421-A1 | 3-(Piperazinylbenzylidenyl)-2-indolinone compounds and derivatives as protein tyrosine kinase inhibitors | SUGEN, INC. | 2003-04-10 | — | — | US | claimed |
| CN-108546224-B | Process for the manufacture of nitriles and their corresponding amines | 中国石化扬子石油化工有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-108530243-B | Process for the manufacture of nitriles and their corresponding amines | 中国石化扬子石油化工有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-108546223-B | Process for the manufacture of nitriles and their corresponding amines | 中国石化扬子石油化工有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-108558589-B | Process for the manufacture of nitriles and their corresponding amines | 中国石化扬子石油化工有限公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-107930696-B | Application of rare earth trimethyl cyclopentadienyl complex in catalyzing hydroboration reaction of imine and borane | 苏州大学 | 2020-02-11 | — | — | CN | disclosed |
| CN-105829922-B | Polymer composition and the method for manufacturing ophthalmic lens using the polymer composition | 依视路国际公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-105431283-B | Increasing material manufacturing for transparent glasses piece | 依视路国际公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-109722260-A | Light orientation aligning agent for liquid crystal, liquid crystal orientation film and its application and azobenzene derivatives, diamines and polymer | 捷恩智株式会社 | 2019-05-07 | — | — | CN | disclosed |
| CN-107887616-A | A kind of oxidation reduction catalyst of novel transition metal modification and preparation method thereof | 中国石油大学(华东) | 2018-04-06 | — | — | CN | disclosed |
| US-6696448-B2 | USEFUL IN THE PREVENTION AND TREATMENT OF PROTEIN TYROSINE KINASE RELATED CELLULAR DISORDERS SUCH AS CANCER, DIABETES, AUTOIMMUNE DISORDERS, HYPERPROLIFERATIVE DISORDERS SUCH AS RHEUMATOID ARTHRITIS AND INFLAMMATORY DISORDERS | SUGEN, INC. | 2004-02-24 | — | — | US | disclosed |
| US-20030069421-A1 | 3-(Piperazinylbenzylidenyl)-2-indolinone compounds and derivatives as protein tyrosine kinase inhibitors | SUGEN, INC. | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069421-A1 | 3-(Piperazinylbenzylidenyl)-2-indolinone compounds and derivatives as protein tyrosine kinase inhibitors | ABL1, ERBB2, PTK2B | ALDH1A1 1507/4885HTT 3509/4885CYP1A2 3184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.