Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297259 | 0.86 | POLB (0.45) | TDP1SIRT1GAAPOLBMAPT | |
| SCHEMBL11296539 | 0.85 | MAPT (0.49) | TDP1GAAPOLBMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL11289242 | 0.84 | POLB (0.44) | TDP1SIRT1GAAPOLBMAPT | |
| Hydrochloric Acid SCHEMBL11288940 | 0.84 | MAPT (0.47) | TDP1GAAPOLBMAPTMEN1 | |
| SCHEMBL11291070 | 0.83 | NPC1 (0.48) | TDP1GAARXFP1MAPTMEN1 | |
| SCHEMBL11296742 | 0.83 | TDP1 (0.43) | TDP1SIRT1GAAPOLBMAPT | |
| SCHEMBL11287507 | 0.83 | GAA (0.47) | TDP1SIRT1GAAMAPTALDH1A1 | |
| SCHEMBL11287005 | 0.82 | HDAC1 (0.45) | MAPTMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL11319565 | 0.81 | MAPT (0.48) | TDP1GAAMAPTMEN1KMT2A | |
| SCHEMBL11288662 | 0.81 | KMT2A (0.37) | GAAPOLBRXFP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |