Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288356 | 0.89 | MAPT (0.48) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11292931 | 0.89 | MAPT (0.51) | TTRKMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11292035 | 0.88 | MAPT (0.53) | HDAC1KEAP1MEN1KMT2AMAPT | |
| SCHEMBL11290937 | 0.85 | KMT2A (0.45) | HDAC1MEN1KMT2AMAPT | |
| SCHEMBL11319565 | 0.85 | MAPT (0.48) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11287081 | 0.85 | NPC1 (0.50) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11296456 | 0.85 | ALDH1A1 (0.43) | MEN1KMT2AMAPTNPC1 | |
| SCHEMBL11294333 | 0.85 | MAPT (0.49) | MEN1KMT2AMAPTNPC1TSHR | |
| SCHEMBL11294809 | 0.82 | TDP1 (0.44) | HDAC1TTRMEN1KMT2AMAPT | |
| SCHEMBL11293489 | 0.81 | KDM4E (0.56) | KMT2AMAPTNPC1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |