Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11289242 | 0.99 | POLB (0.44) | POLBTDP1MAPTCNR1CNR2 | |
| SCHEMBL11294809 | 0.86 | TDP1 (0.44) | POLBTDP1MAPTMEN1KMT2A | |
| SCHEMBL11296539 | 0.85 | MAPT (0.49) | POLBTDP1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11288940 | 0.84 | MAPT (0.47) | POLBTDP1MAPTMEN1KMT2A | |
| SCHEMBL11296742 | 0.83 | TDP1 (0.43) | POLBTDP1MAPTCNR1CNR2 | |
| SCHEMBL11287507 | 0.83 | GAA (0.47) | TDP1MAPTLMNAMAPK1SIRT1 | |
| SCHEMBL11291070 | 0.83 | NPC1 (0.48) | TDP1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL11131815 | 0.82 | MAPT (0.51) | TDP1MAPTCNR1CNR2MEN1 | |
| SCHEMBL11291087 | 0.81 | MAPT (0.48) | POLBTDP1MAPTMEN1KMT2A | |
| SCHEMBL11289409 | 0.80 | KDM4E (0.53) | POLBTDP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | claimed |
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |