Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10552990 | 0.92 | TDP1 (0.37) | KMT2ASMN1; SMN2MAPTPDE3ASLC22A6 | |
| SCHEMBL10557134 | 0.84 | NAAA (0.42) | KMT2ASMN1; SMN2MAPTPDE3ASLC22A6 | |
| SCHEMBL11058890 | 0.83 | MAPT (0.40) | KMT2AMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL10547026 | 0.79 | KMT2A (0.44) | KMT2ASMN1; SMN2TDP1MEN1ALDH1A1 | |
| SCHEMBL10556576 | 0.76 | TDP1 (0.41) | KMT2AMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL11292991 | 0.74 | PTPRB (0.34) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11288343 | 0.74 | XIAP (0.34) | KMT2AMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL11285422 | 0.73 | — | — | |
| SCHEMBL10552749 | 0.71 | TDP1 (0.39) | KMT2AMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL10416585 | 0.71 | MEN1 (0.41) | KMT2AMAPTPDE3ASLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053387-A1 | Method of preparing 1-sulfo-2-oxoazetidine derivatives and intermediates therefor | Takeda Chemical Industries, Ltd. (JP) | 1982-06-09 | — | — | EP | disclosed |
| EP-0021678-A1 | 1-Sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |