⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27270005 | 1.00 | — | — | |
| SCHEMBL5861940 | 0.80 | HSD17B10 (0.41) | — | |
| SCHEMBL3049838 | 0.79 | — | — | |
| SCHEMBL8471198 | 0.78 | — | — | |
| SCHEMBL103243 | 0.78 | — | — | |
| SCHEMBL7744271 | 0.78 | — | — | |
| SCHEMBL3686870 | 0.78 | — | — | |
| SCHEMBL11328624 | 0.77 | ECE1 (0.40) | — | |
| SCHEMBL21319394 | 0.77 | HDAC7 (0.39) | — | |
| SCHEMBL13876693 | 0.76 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002505917-A | — | — | 2002-02-26 | — | — | JP | claimed |
| EP-1061963-A1 | PROTEASE INHIBITORS IN ABSORBENT ARTICLES | THE PROCTER & GAMBLE COMPANY (US) | 2000-12-27 | — | — | EP | claimed |
| WO-1999045974-A1 | PROTEASE INHIBITORS IN ABSORBENT ARTICLES | THE PROCTER & GAMBLE COMPANY (US) | 1999-09-16 | — | — | WO | claimed |
| EP-0577473-B1 | Reducing cosmetic composition for the permanent deformation of hair based on a mercaptoalkylamino-amide and process for the permanent deformation of hair | OREAL (FR) | 1995-12-20 | — | — | EP | claimed |
| EP-0577473-A1 | Reducing cosmetic composition for the permanent deformation of hair based on a mercaptoalkylamino-amide and process for the permanent deformation of hair | L'OREAL (FR) | 1994-01-05 | — | — | EP | claimed |
| US-20240425450-A1 | SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS | Artizan Biosciences, Inc. | 2024-12-26 | — | — | US | disclosed |
| WO-2024054845-A1 | MACROCYCIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |
| US-20230357139-A1 | SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS | Artizan Biosciences, Inc. | 2023-11-09 | — | — | US | disclosed |
| US-11696912-B2 | Charged ion channel blockers and methods for use | Nocion Therapeutics, Inc. (US) | 2023-07-11 | — | — | US | disclosed |
| US-20210299112-A1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | NOCION THERAPEUTICS INC (US) | 2021-09-30 | — | — | US | disclosed |
| CN-107382856-B | Novel polysubstituted isoquinoline derivative and synthetic method thereof | 江苏理工学院 | 2020-07-28 | — | — | CN | disclosed |
| WO-2016049565-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF RAS | ARAXES PHARMA LLC (US) | 2016-03-31 | — | — | WO | disclosed |
| EP-0855419-A1 | Process for coating polymeric gel | ELF ATOCHEM S.A. (FR) | 1998-07-29 | — | — | EP | disclosed |
| EP-0822012-A1 | Coating on metallic surfaces and use on tubes and cables | ELF ATOCHEM S.A. (FR) | 1998-02-04 | — | — | EP | disclosed |
| EP-0814487-A1 | Impregnants for self-healing capacitors | ELF ATOCHEM S.A. (FR) | 1997-12-29 | — | — | EP | disclosed |
| EP-0784070-A1 | Plasticised compound based on polyalcohol with controlled viscosity | ELF ATOCHEM S.A. (FR) | 1997-07-16 | — | — | EP | disclosed |
| EP-0577473-B1 | Reducing cosmetic composition for the permanent deformation of hair based on a mercaptoalkylamino-amide and process for the permanent deformation of hair | OREAL (FR) | 1995-12-20 | — | — | EP | disclosed |
| EP-0676432-A1 | Polyurethane elastomer formulation on the basis of polydiene polyols and castor oil having improved damping properties | ELF ATOCHEM S.A. (FR) | 1995-10-11 | — | — | EP | disclosed |
| EP-0577473-A1 | Reducing cosmetic composition for the permanent deformation of hair based on a mercaptoalkylamino-amide and process for the permanent deformation of hair | L'OREAL (FR) | 1994-01-05 | — | — | EP | disclosed |
| US-4347342-A | Process for initiating radical reactions employing hydroximic acid derivatives | AKZONA INCORPORATED (US) | 1982-08-31 | — | — | US | disclosed |