SCHEMBL5861940

SCHEMBL5861940

CCC(C)C(=O)NC(=O)C(C)CC

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.41
TSHR P16473 3/20 0.40
USP2 O75604 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA14 Q9ULX7 1/20 0.40
KDM4E B2RXH2 3/20 0.39
KMT2A Q03164 2/20 0.39
GLS O94925 2/20 0.39
MEN1 O00255 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SLC15A1 P46059 1/20 0.39
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
ALDH1A1 P00352 2/20 0.37
RAB9A P51151 1/20 0.37
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13040562 0.87 HSD17B10 (0.38) HSD17B10TSHRUSP2CA1CA2
SCHEMBL6023207 0.87 HSD17B10 (0.38) HSD17B10TSHRUSP2CA1CA2
SCHEMBL24131977 0.85 CYP2C9 (0.41) HSD17B10TSHRUSP2CA1CA2
SCHEMBL3653427 0.85 CRBN (0.40) HSD17B10TSHRUSP2CA1CA2
SCHEMBL28787185 0.83 LMNA (0.37) HSD17B10TSHRUSP2CA1CA2
SCHEMBL7284685 0.82 DPP4 (0.41) SLC15A1
SCHEMBL13285717 0.81 TAS2R38 (0.44) HSD17B10TSHRUSP2CA1CA2
SCHEMBL13109159 0.81 CA1 (0.38) HSD17B10TSHRUSP2CA1CA2
SCHEMBL1129487 0.80
SCHEMBL3686870 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170355833-A1 STERICALLY HINDERED AMINE AND OXYALKYL AMINE LIGHT STABILIZERS 3M INNOVATIVE PROPERTIES COMPANY 2017-12-14 US disclosed
US-7094516-B2 Benzobisazole compound and optical recording medium containing the compound MITSUI CHEMICALS, INC. (JP) 2006-08-22 US disclosed
US-20060088786-A1 Rewritable optical information recording medium, recording and reproducing methods, as well as recording and reproducing apparatus MITSUI CHEMICALS, INC. (JP) 2006-04-27 US disclosed
EP-1180765-B1 Optical recording medium and porphycene compound MITSUI CHEMICALS INC (JP) 2005-04-06 EP disclosed
EP-1484191-A1 REWRITABLE OPTICAL INFORMATION RECORDING MEDIUM AND RECORDING/REPRODUCING METHOD, RECORDING/REPRODUCING DEVICE Sony Corporation (JP) 2004-12-08 EP disclosed
US-6627288-B1 Optical recording medium and porphycene compound MITSUI CHEMICALS, INC. (JP) 2003-09-30 US disclosed
US-20030091931-A1 Benzbisazole compound and optical recording medium containing the compound MITSUI CHEMICALS, INC. (JP) 2003-05-15 US disclosed
EP-1180765-A1 Optical recording medium and porphycene compound Mitsui Chemicals, Inc. (JP) 2002-02-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030091931-A1 Benzbisazole compound and optical recording medium containing the compound DAO, CACNA1I, KCNB2 HSD17B10 1347/4885TSHR 3514/4885USP2 4817/4885
US-20060088786-A1 Rewritable optical information recording medium, recording and reproducing methods, as well as recording and reproducing apparatus ALPG, TRPC6, GNRHR HSD17B10 4128/4885TSHR 1237/4885USP2 4630/4885
US-20170355833-A1 STERICALLY HINDERED AMINE AND OXYALKYL AMINE LIGHT STABILIZERS SIGMAR1, AAAS, TAAR1 HSD17B10 4351/4885TSHR 1389/4885USP2 574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.