Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11302564 | 0.95 | HTT (0.45) | HTTTDP1L3MBTL1SMN1; SMN2EPAS1 | |
| SCHEMBL9859653 | 0.92 | HTT (0.46) | HTTTDP1L3MBTL1SMN1; SMN2EPAS1 | |
| SCHEMBL11290154 | 0.91 | HTT (0.47) | HTTTDP1L3MBTL1SMN1; SMN2EPAS1 | |
| SCHEMBL11299945 | 0.90 | HTT (0.49) | HTTTDP1L3MBTL1SMN1; SMN2EPAS1 | |
| SCHEMBL11292165 | 0.87 | HTT (0.49) | HTTTDP1L3MBTL1SMN1; SMN2EPAS1 | |
| SCHEMBL11294592 | 0.87 | HTT (0.49) | HTTTDP1L3MBTL1SMN1; SMN2EPAS1 | |
| SCHEMBL11299921 | 0.85 | PKM (0.50) | HTTTDP1L3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11297727 | 0.84 | HTT (0.53) | HTTTDP1L3MBTL1SMN1; SMN2EPAS1 | |
| SCHEMBL11301461 | 0.84 | HTT (0.49) | HTTTDP1L3MBTL1SMN1; SMN2EPAS1 | |
| SCHEMBL11296514 | 0.82 | HTT (0.47) | HTTTDP1L3MBTL1SMN1; SMN2EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356325-A | Process for preparation of acetylene terminated sulfones, oligomers and precursors therefor | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-10-26 | — | — | US | disclosed |