Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292165 | 0.95 | HTT (0.49) | HTTSMN1; SMN2TDP1L3MBTL1PKM | |
| SCHEMBL11299921 | 0.93 | PKM (0.50) | HTTSMN1; SMN2TDP1L3MBTL1PKM | |
| SCHEMBL11301461 | 0.92 | HTT (0.49) | HTTSMN1; SMN2TDP1L3MBTL1PKM | |
| SCHEMBL11295332 | 0.92 | HTT (0.46) | HTTSMN1; SMN2TDP1L3MBTL1PKM | |
| SCHEMBL11296514 | 0.89 | HTT (0.47) | HTTSMN1; SMN2TDP1L3MBTL1PKM | |
| SCHEMBL11293471 | 0.88 | HTT (0.46) | HTTSMN1; SMN2TDP1L3MBTL1PKM | |
| SCHEMBL11297458 | 0.88 | HTT (0.43) | HTTSMN1; SMN2TDP1L3MBTL1PKM | |
| SCHEMBL11297725 | 0.87 | HTT (0.48) | HTTSMN1; SMN2TDP1L3MBTL1PKM | |
| SCHEMBL11302564 | 0.87 | HTT (0.45) | HTTSMN1; SMN2TDP1L3MBTL1PKM | |
| SCHEMBL11299945 | 0.85 | HTT (0.49) | HTTSMN1; SMN2TDP1L3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446720-A2 | Novel brominated phenoxy compounds and processes for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |