SCHEMBL11295418

SCHEMBL11295418

CC1CC(c2ccc(Br)cc2)c2cc(Br)ccc21

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 5/20 0.40
HTR2C P28335 5/20 0.40
HTR2B P41595 5/20 0.40
HRH3 Q9Y5N1 4/20 0.40
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
KDM1A O60341 7/20 0.37
KCNH2 Q12809 2/20 0.37
MAOB P27338 2/20 0.37
RCOR1 Q9UKL0 2/20 0.37
KDM1B Q8NB78 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11298526 0.84 HTR2A (0.51) HTR2AHTR2CHTR2BHRH3KDM1A
SCHEMBL11290967 0.79 KDM1A (0.50) HTR2AHTR2CHTR2BHRH3KDM1A
SCHEMBL11308474 0.78 HTR2C (0.42) HTR2AHTR2CHTR2BHRH3CA1
SCHEMBL11296622 0.76 HTR2A (0.56) HTR2AHTR2CHTR2BHRH3KDM1A
SCHEMBL11295350 0.75 HTR2A (0.41) HTR2AHTR2CHTR2BHRH3
SCHEMBL11767618 0.72 HPGD (0.38)
SCHEMBL14804298 0.69 HTR2A (0.54) HTR2AHTR2CHTR2BHRH3KDM1A
SCHEMBL7599978 0.67 SIGMAR1 (0.47) HTR2AHTR2CHTR2BHRH3
SCHEMBL7599981 0.67 SIGMAR1 (0.47) HTR2AHTR2CHTR2BHRH3
SCHEMBL2036589 0.67 SIGMAR1 (0.47) HTR2AHTR2CHTR2BHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0004591-B1 SHELL CATALYST, PROCESS FOR ITS PREPARATION AND ITS USE FOR THE PREPARATION OF ANTHRAQUINONES BASF Aktiengesellschaft (DE) 1982-03-31 EP disclosed
EP-0004591-A1 Shell catalyst, process for its preparation and its use for the preparation of anthraquinones BASF Aktiengesellschaft (DE) 1979-10-17 EP disclosed