SCHEMBL11298526

SCHEMBL11298526

CC1CC(c2ccc(Br)cc2)c2ccccc21

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.51
HTR2C P28335 2/20 0.51
HTR2B P41595 2/20 0.51
HRH3 Q9Y5N1 2/20 0.51
KDM1A O60341 1/20 0.38
KCNH2 Q12809 1/20 0.38
KDM1B Q8NB78 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14804298 0.86 HTR2A (0.54) HTR2AHTR2CHTR2BHRH3KDM1A
SCHEMBL7599978 0.84 SIGMAR1 (0.47) HTR2AHTR2CHTR2BHRH3
SCHEMBL7609588 0.84 SIGMAR1 (0.47) HTR2AHTR2CHTR2BHRH3
SCHEMBL2036589 0.84 SIGMAR1 (0.47) HTR2AHTR2CHTR2BHRH3
SCHEMBL7609590 0.84 SIGMAR1 (0.47) HTR2AHTR2CHTR2BHRH3
SCHEMBL7599981 0.84 SIGMAR1 (0.47) HTR2AHTR2CHTR2BHRH3
SCHEMBL11295418 0.84 HTR2A (0.40) HTR2AHTR2CHTR2BHRH3KDM1A
SCHEMBL11291691 0.81 HTR2A (0.53) HTR2AHTR2CHTR2BHRH3
SCHEMBL8527042 0.81 ESR2 (0.40)
SCHEMBL11296622 0.81 HTR2A (0.56) HTR2AHTR2CHTR2BHRH3KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0004591-B1 SHELL CATALYST, PROCESS FOR ITS PREPARATION AND ITS USE FOR THE PREPARATION OF ANTHRAQUINONES BASF Aktiengesellschaft (DE) 1982-03-31 EP disclosed
US-4255285-A FOR THE CATALYTIC OXIDATION OF A 1-PHENYLINDAN TO AN ANTHRAQUINONE; ATOMIZING AN AQUEOUS VANADIUM COMPOUND TO COAT AND ROAST MOVING CARRIER PARTICLES BASF AKTIENGESELLSCHAFT (DE) 1981-03-10 US disclosed
EP-0004591-A1 Shell catalyst, process for its preparation and its use for the preparation of anthraquinones BASF Aktiengesellschaft (DE) 1979-10-17 EP disclosed