Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | USP8 | P40818 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11295450 | 1.00 | CA1 (0.43) | CA1CA2CA7CA9MALT1 | |
| SCHEMBL12512832 | 0.78 | ALDH1A1 (0.46) | CA1CA2CA7CA9KDM4E | |
| SCHEMBL11293009 | 0.78 | ALDH1A1 (0.46) | CA1CA2CA7CA9MALT1 | |
| SCHEMBL11292464 | 0.78 | ALDH1A1 (0.46) | CA1CA2CA7CA9MALT1 | |
| SCHEMBL18948937 | 0.75 | CA1 (0.43) | CA1CA2CA7CA9MALT1 | |
| SCHEMBL21098267 | 0.72 | CA1 (0.41) | CA1CA2CA7CA9MALT1 | |
| SCHEMBL11292642 | 0.72 | PDK2 (0.44) | CA1CA2CA7CA9KDM4E | |
| SCHEMBL8829493 | 0.69 | PGR (0.40) | KDM4EMAPTCYP3A4ALDH1A1MEN1 | |
| SCHEMBL11305762 | 0.69 | PDK2 (0.45) | CA1CA7CA9ALKMAPT | |
| SCHEMBL11305757 | 0.69 | PDK2 (0.45) | CA1CA7CA9ALKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005821-B1 | INDANAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1982-12-08 | — | — | EP | disclosed |
| EP-0005821-A1 | Indanamine derivatives, process for their preparation and medicaments containing them | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1979-12-12 | — | — | EP | disclosed |