Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 6/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300475 | 0.86 | HDAC8 (0.34) | HDAC8ESR1 | |
| SCHEMBL11295520 | 0.85 | HDAC8 (0.32) | HDAC8 | |
| SCHEMBL11296572 | 0.80 | PSMB5 (0.35) | PSMB5MMP3 | |
| SCHEMBL11303227 | 0.79 | PSMB5 (0.37) | PSMB5 | |
| SCHEMBL11213904 | 0.78 | ESR1 (0.42) | ESR1MMP3 | |
| SCHEMBL11294159 | 0.78 | PSMB5 (0.32) | PSMB5 | |
| SCHEMBL11301861 | 0.78 | GPR84 (0.33) | PSMB5MMP3 | |
| SCHEMBL11301530 | 0.77 | PPARA (0.38) | PSMB5 | |
| SCHEMBL11294066 | 0.77 | SMN1; SMN2 (0.41) | ESR1 | |
| SCHEMBL11299265 | 0.77 | ABCB1 (0.38) | PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261732-A | Alkyl and alkoxyalkyl N-3-alkyl and N-3,5-dialkylbenzoyl-N-isopropylaminoacetate herbicides | PPG INDUSTRIES, INC. (US) | 1981-04-14 | — | — | US | disclosed |