Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300191 | 0.86 | F10 (0.34) | SMN1; SMN2TSHR | |
| SCHEMBL11339619 | 0.86 | CNR2 (0.33) | SMN1; SMN2L3MBTL1NPC1RAB9AHPGD | |
| SCHEMBL11213904 | 0.86 | ESR1 (0.42) | SMN1; SMN2L3MBTL1ESR1LMNACYP1A2 | |
| SCHEMBL11303206 | 0.83 | MEN1 (0.37) | ESR1 | |
| SCHEMBL11296776 | 0.83 | REN (0.33) | CYP3A4TP53 | |
| SCHEMBL11398511 | 0.82 | PLA2G2A (0.44) | L3MBTL1LMNATSHRMAPK1 | |
| SCHEMBL11302460 | 0.82 | MEN1 (0.31) | LMNATP53MAPK1 | |
| SCHEMBL11297857 | 0.77 | REN (0.39) | SMN1; SMN2LMNA | |
| SCHEMBL11294344 | 0.77 | CYP4F2 (0.43) | SMN1; SMN2L3MBTL1NPC1RAB9AHPGD | |
| SCHEMBL11295563 | 0.77 | HDAC8 (0.33) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261732-A | Alkyl and alkoxyalkyl N-3-alkyl and N-3,5-dialkylbenzoyl-N-isopropylaminoacetate herbicides | PPG INDUSTRIES, INC. (US) | 1981-04-14 | — | — | US | disclosed |