Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.38 |
| ▸ | MPL | P40238 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | HPD | P32754 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443266 | 0.85 | LMNA (0.45) | POLBMAPTNOTUMKDM4EMPL | |
| SCHEMBL11651603 | 0.75 | KDM4E (0.58) | POLBMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL11310457 | 0.74 | LMNA (0.45) | MAPTNOTUMKDM4EMPLALDH1A1 | |
| SCHEMBL7890105 | 0.72 | KDM4E (0.41) | POLBKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11410806 | 0.70 | MYC (0.49) | POLBNOTUMKDM4EALDH1A1CYP3A4 | |
| SCHEMBL11417116 | 0.70 | F2 (0.33) | KDM4ENPSR1 | |
| SCHEMBL6875333 | 0.68 | KDM4E (0.40) | POLBMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11316417 | 0.68 | LMNA (0.44) | POLBALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9401741 | 0.68 | CYP2C19 (0.36) | MAPTMPLALDH1A1CYP2C19MEN1 | |
| SCHEMBL10955294 | 0.67 | ALDH1A1 (0.37) | POLBMAPTSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013936-B1 | REACTIVE AZO DYESTUFFS, THEIR PREPARATION AND THEIR USE IN DYEING MATERIALS CONTAINING HYDROXYL GROUPS AND AMIDE GROUPS | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| US-4299764-A | Azo reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-11-10 | — | — | US | disclosed |
| EP-0013936-A1 | Reactive azo dyestuffs, their preparation and their use in dyeing materials containing hydroxyl groups and amide groups | BAYER AG (DE) | 1980-08-06 | — | — | EP | disclosed |