SCHEMBL1129630

SCHEMBL1129630

SCc1ccc(-c2ccncc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
LMNA P02545 1/20 0.55
CYP17A1 P05093 7/20 0.48
CYP11B1 P15538 6/20 0.48
CYP11B2 P19099 5/20 0.48
CYP19A1 P11511 3/20 0.48
CYP3A4 P08684 3/20 0.48
NOTUM Q6P988 1/20 0.46
CYP21A2 P08686 1/20 0.46
LSS P48449 1/20 0.46
KIF11 P52732 2/20 0.44
IDO1 P14902 4/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
QDPR P09417 1/20 0.41
PRKCI P41743 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL27170372 0.86 IDO1 (0.50) MAPTLMNACYP17A1CYP11B1CYP11B2
SCHEMBL451748 0.84
SCHEMBL17756332 0.84 IDO1 (0.58) LMNAIDO1
SCHEMBL441726 0.84 IDO1 (0.58) LMNAIDO1
SCHEMBL17756329 0.84 IDO1 (0.58) LMNAIDO1
Hydrochloric Acid SCHEMBL1345387 0.81
SCHEMBL1129624 0.81 CYP17A1 (0.52) MAPTLMNACYP17A1CYP11B1CYP11B2
SCHEMBL135626 0.78 MAPT (0.92) MAPTLMNACYP3A4NOTUMKIF11
SCHEMBL10000032 0.78 MAPT (0.92) MAPTLMNACYP3A4NOTUMKIF11
SCHEMBL28280648 0.78 MAPT (0.92) MAPTLMNACYP3A4NOTUMKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9757767-B2 Device and method for producing highly porous, crystalline surface coatings KARLSRUHER INSTITUT FUER TECHNOLOGIE (DE) 2017-09-12 US disclosed
EP-2714286-B1 DEVICE AND METHOD FOR PRODUCING HIGHLY POROUS, CRYSTALLINE SURFACE COATINGS KARLSRUHER INST FÜR TECHNOLOGIE (DE) 2016-03-02 EP disclosed
US-8932976-B2 Preparation of catalyst for bisphenols production DOW GLOBAL TECHNOLOGIES LLC (US) 2015-01-13 US disclosed
US-20140302304-A1 DEVICE AND METHOD FOR PRODUCING HIGHLY POROUS, CRYSTALLINE SURFACE COATINGS KARLSRUHER INSTITUT FUER TECHNOLOGIE (DE) 2014-10-09 US disclosed
WO-2012163854-A1 DEVICE AND METHOD FOR PRODUCING HIGHLY POROUS, CRYSTALLINE SURFACE COATINGS Karlsruher Institut für Technologie (DE) 2012-12-06 WO disclosed
EP-2158040-B1 PREPARATION OF CATALYST FOR BISPHENOLS PRODUCTION DOW GLOBAL TECHNOLOGIES INC (US) 2011-02-16 EP disclosed
US-20100152028-A1 PREPARATION OF CATALYST FOR BISPHENOLS PRODUCTION DOW GLOBAL TECHNOLOGIES LLC 2010-06-17 US disclosed
CN-101678354-A The Preparation of catalysts that is used for bisphenol production DOW GLOBAL TECHNOLOGIES INC 2010-03-24 CN disclosed
EP-2158040-A1 PREPARATION OF CATALYST FOR BISPHENOLS PRODUCTION Dow Global Technologies Inc. (US) 2010-03-03 EP disclosed
WO-2008157025-A1 PREPARATION OF CATALYST FOR BISPHENOLS PRODUCTION DOW GLOBAL TECHNOLOGIES INC. (US) 2008-12-24 WO disclosed