Pyridine

Pyridine

SCHEMBL27170372

SCc1ccc(-c2ccc(CS)cc2)cc1.c1ccncc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.50
MKNK1 Q9BUB5 1/20 0.42
MKNK2 Q9HBH9 1/20 0.42
CYP2A6 P11509 1/20 0.42
NOTUM Q6P988 1/20 0.42
TSHR P16473 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP17A1 P05093 7/20 0.41
CYP11B1 P15538 7/20 0.41
CYP11B2 P19099 7/20 0.41
CYP3A4 P08684 5/20 0.41
CYP19A1 P11511 5/20 0.41
TAAR1 Q96RJ0 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1129630 0.86 MAPT (0.55) IDO1NOTUMCYP17A1CYP11B1CYP11B2
SCHEMBL1129909 0.81 CYP2A6 (0.67) MKNK1MKNK2CYP2A6CYP17A1CYP11B1
SCHEMBL14705252 0.80 IDO1 (0.68) IDO1TSHRTDP1CYP3A4TAAR1
SCHEMBL1411374 0.80 IDO1 (0.68) IDO1TSHRTDP1CYP3A4TAAR1
SCHEMBL441726 0.80 IDO1 (0.58) IDO1TSHRTAAR1LMNA
SCHEMBL17756332 0.80 IDO1 (0.58) IDO1TSHRTAAR1LMNA
SCHEMBL17756329 0.80 IDO1 (0.58) IDO1TSHRTAAR1LMNA
SCHEMBL451748 0.75
SCHEMBL6850529 0.73 ADRB2 (0.63) IDO1CYP2A6CYP3A4
SCHEMBL1129364 0.72 KDM4E (0.50) IDO1CYP2A6TDP1CYP19A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240085335-A1 MULTIPLEXED RAMAN MOLECULAR IMAGING UNIVERSITY OF SOUTHERN CALIFORNIA 2024-03-14 US disclosed